Sulfodene Hot Spot & Itch Relief Medicated Spray 8oz for Dogs. Formerly came in 4oz liquid. The only FDA-approved aid in the treatment of hot spots. Non-stinging, provides fast relief from itching caused by hot spots, flea bites and allergies. First aid for scrapes and abrasions, too! Now comes in an easy to use spray. Active Ingredients: Benzoyl Alcohol-2%, Licocaine Hydrochloride - 0.5%, Benzalkonium Chloride 0.05%.